Characterization of bleeding in thrombotic thrombocytopenic purpura in the precaplacizumab era: a retrospective nationwide analysis.

Older age (≥60 years) was not associated with major bleeding in our study though a previous analysis of the NIS database, which focused on the impact of age on the delays in initiation of TPE for iTTP, reported marginal significance of age ≥ 60 years as a risk factor on major bleeding [ 22 ].

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