16 , 61 , 62 A 2024 review and meta-analysis found global prevalence rates of advanced liver fibrosis and cirrhosis at 3.3% and 1.3%, respectively, with an increasing trend since 2016. 63 The fundamental process underlying liver fibrosis is characterized by the activation of hepatic stellate cells (HSCs), which secrete ECM components, thereby contributing to both the development of liver fibrosis and the remodeling of liver architecture. 15 There are specific mechanisms and signaling pathways involved in this process.
← all excerpts
Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis.
1
—
—