highly significantp < 0.001
Similarly, groups treated with 400 mg/kg dose showed highly significant ITL on 7 th , 14 th and 28 th day observations (p < 0.001). 3.1.9 Open field maze test In the open field maze test, significant declined ambulatory movements were observed for control group animals on 7 th , 14 th and 28 th day of surveillance (p < 0.001).