A genome-wide scan of non-coding RNAs and enhancers for refractive error and myopia.

Hum Genet · 2025 · PMC11754329 · PMID 39774722

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

borderline significantP = 0.053so close (0.05 < p ≤ 0.1)

The GRS of lncRNAs was significantly associated with AL progression between 6 and 9 years, 9–13 years and AL/CR at 13 years and borderline significant with RE (FDR adjusted P = 0.053).

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near significanceno p-value reported

The association between the GRS of miRNA binding sites and AL progression between 9 and 12 years showed near significance (nominal significance but not anymore after FDR correction), which warrants replication of the associations with GRS and the individual risk variants.

also in 505 other papers

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