Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness.

BMC Biol · 2025 · PMC11756181 · PMID 39849498

Europe PMC DOI

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0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a trend towards significancep = 0.06so close (0.05 < p ≤ 0.1)

This change was statistically significant in media derived from MDA-MB-231 cells ( p < 0.05), and there was a trend towards significance in media derived from BT-549 cells ( p = 0.06).

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highly significantno p-value reported

A differential expression analysis between pre-miR-1307 overexpressing cells and control cells revealed a mild, but consistent and highly significant upregulation of all three detected 5′isomiRs of pre-miR-1307, whereas no global changes in 5′isomiR expression could be observed (Fig. 2 b).

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