Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.

Front Immunol · 2024 · PMC11757129 · PMID 39867884

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an increasing trendno p-value reported

In peripheral blood, we found the proportion of CD25 + Foxp3 + T cells in the UC mice increased after inhibitor intervention, upon examination of CD4 + IL-17A + T cells in UC mice showed an increasing trend but without statistical significance ( Figure 3G ).

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