Individual and sex differences in frontloading behavior and approach- avoidance conflict preference predict addiction-like ethanol seeking in rats.

FR3_15_min_con ( t (45) = -3.399, p < 0.01), FS_Score ( t (45) = 4.836, p < 0.001), Onset_Skew ( t (45) = -3.255, p < 0.01), Binge ( t (45) = 2.337, p < 0.05) and Sex*Conflict_Pref ( t (45) = -3.071, p < 0.01) were all significant predictors of Ext_Score, while the Sex term ( t (45) = -1.826, p = 0.074) was marginally significant, suggesting less persistent pressing in extinction in males, and the Conflict_Pref term was insignificant ( t (45) = 1.349, p = 0.184) but remained in the model as it was part of the interaction.

also in 26,082 other papers