Multiomics approach identifies dysregulated lipidomic and proteomic networks in Parkinson's disease patients mutated in TMEM175.

NPJ Parkinsons Dis · 2025 · PMC11760379 · PMID 39856101

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We also observed a highly significant reduced level of proteins involved in autophagic-lysosomal pathways such as CATK, CATF and CATL1, which are involved in protein degradation 20 and RAB7L, an autophagy-related protein, recently associated with PD 21 .

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