Islet NO-Synthases, extracellular NO and glucose-stimulated insulin secretion: Possible impact of neuronal NO-Synthase on the pentose phosphate pathway.

However, application of SITS converted the stimulatory action of NO at 2 μM to a highly significant inhibitory effect, and the absence of an effect at 20 μM NO in untreated islets was now inhibitory in the presence of SITS.

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