Oxidative Stress and Risk of Dementia in Older Patients with Depression: A Longitudinal Cohort Study Using Plasma Biomarkers.

Medicina (Kaunas) · 2025 · PMC11766485 · PMID 39859090

Europe PMC DOI

hedged sentence

0.0652

closest p · 1.3× alpha

0.0652

boldest claim

The sentences

a trend toward significancep = 0.0652so close (0.05 < p ≤ 0.1)

showed a trendp = 0.0652so close (0.05 < p ≤ 0.1)

Protein carbonyl showed a trend toward significance (HR, 2.92; 95% CI, 0.94–9.11; p = 0.0652), while other biomarkers, including F2-isoprostanes, 4-HNE, MDA, and 8-OHdG, did not show significant associations with AD conversion.

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