The interesting DEGs with extremely significant changes in the geldanamycin synthesis pathway were selected for validation, and the main pathways included the ansamycin synthesis pathway, glycolysis pathway (EMP), pantothenate and CoA biosynthesis pathway, citrate cycle (TCA cycle), valine, leucine, and isoleucine degradation pathway, pyruvate metabolism, fatty acid biosynthesis pathway, and pentose phosphate pathway (PPP).
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Improving Geldanamycin Production in <i>Streptomyces geldanamycininus</i> Through UV Mutagenesis of Protoplast.
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