Specific modulation of 28S_Um2402 rRNA 2'-<i>O</i>-ribose methylation as a novel epitranscriptomic marker of ZEB1-induced epithelial-mesenchymal transition in different mammary cell contexts.

NAR Cancer · 2025 · PMC11773364 · PMID 39877292

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of borderline significanceno p-value reported

Nevertheless, while no significant correlation was observed for TWIST1, a significant inverse correlation was observed between 2′Ome levels at the 28S_Um2402 rRNA site and the expression of ZEB1, similar trend of borderline significance being observed with ZEB2 overexpression (Fig. 5C – E ).

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Specific modulation of 28S_Um2402 rRNA 2'-&lt;i&gt;O&lt;/i&gt;-ribose methylation as a novel epitranscriptomic marker of ZEB1-induced epithelial-mesenchymal transition in different mammary cell contexts.

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Specific modulation of 28S_Um2402 rRNA 2'-<i>O</i>-ribose methylation as a novel epitranscriptomic marker of ZEB1-induced epithelial-mesenchymal transition in different mammary cell contexts.