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Trajectories of general and central obesity beyond middle age in relation to late-life cognitive decline and dementia.

Obesity (Silver Spring) · 2025 · PMC11774005 · PMID 39873393

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an increasing trendno p-value reported
Similarly, when compared with participants in the low‐stable WC group, indicating a stable and healthy WC (range, 76–79 cm), those in the high‐increasing WC group, showing an increasing trend (range, 115–122 cm), demonstrated an increased risk of developing dementia (OR, 1.57, 95% CI: 1.01 to 2.49) and experienced a swifter cognitive decline (OR: −0.18 [95% CI: −0.28 to −0.07]).

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