Efficacy of Platelet-Rich Plasma in Endoscopic Sinus Surgery for Chronic Sinusitis: A Systematic Review and Meta-Analysis.

Cureus · 2024 · PMC11774301 · PMID 39877770

Europe PMC DOI

hedged sentences

0.0002

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantP = 0.0002actually significant

In sensitivity analysis, after excluding one study, the analysis revealed a highly significant effect in favor of PRP with a homogenous effect (MD = 0.83, 95% CI: 0.39, 1.26, P = 0.0002, I2 = 0%) (Figure 10 ).

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borderline significanceP = 0.05actually significant

Subgroup analysis based on the location of administration showed borderline significance in the middle meatus group (-2.70 (95% CI: -5.35, -0.04), P = 0.05).

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borderline significantno p-value reported

Regarding olfactory function, PRP's potential to regenerate olfactory receptor neurons could explain the borderline significant improvement in olfactory sensation scores observed in our study.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.