Efficacy of innovative systemic treatments in combination with radiotherapy for bone metastases: a GEMO (the European Study Group of Bone Metastases) state of the art.

Cancer Metastasis Rev · 2025 · PMC11775081 · PMID 39875680

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a positive trendno p-value reported

Combining ipilimumab, nivolumab, and standard chemotherapy compared with standard chemotherapy alone showed a positive trend in BoM + in the CheckMate 227 [ 47 ] and CheckMate 9LA [ 48 ] studies, while demonstrating a significant benefit in BoM-.

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