Barely Significant
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Global, Regional, and National Burden of Male Breast Cancer, 1990-2021: A Systematic Analysis for the Global Burden of Disease Study 2021.

Cancer Med · 2025 · PMC11775920 · PMID 39878368

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an increasing trendno p-value reported
Conclusion From 1990 to 2021, the ASIR, ASDR, and ASDALY of MBC have shown significant disparities and an increasing trend.

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a decreasing trendno p-value reported
If the upper limit of both an EAPC and its 95% CI is negative, its corresponding rate shows a decreasing trend; conversely, if the lower limit of both an EAPC and its 95% CI is positive, its corresponding rate shows an increasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.