a decreasing trendP< 0.001
ITSA revealed an immediate decrease in DOT per 100 visits for 3GC (-1.03; 95% confidence interval [CI]: -1.31 to -0.74; P< 0.001 for intercept) and a decreasing trend in FQ and MC during the intervention period (-0.71 and -0.41; 95% CI: -0.54 to -0.27 and -1.18 to -0.25; P< 0.001 and 0.004, respectively).