Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer.

BMC Genomics · 2002 · PMC117791 · PMID 12123529

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highly significantno p-value reported

For example, microarray data showing a 4-fold change derived from low signal intensities may have no statistical significance whereas a 1.4 fold change derived from strong signal intensities may be highly significant in terms of reflecting actual changes in mRNA concentration within a biological sample.

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