p-AKT and p-FoxO3a levels showed a decreasing trend after I/R, whereas Cur increased p-AKT and p-FoxO3a levels in the rat myocardium ( Fig. 9G and H ).
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Curcumin attenuates myocardial ischemia‑reperfusion‑induced autophagy‑dependent ferroptosis via Sirt1/AKT/FoxO3a signaling.
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