Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein.

Fluids Barriers CNS · 2025 · PMC11783731 · PMID 39885527

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an increasing trendno p-value reported

Brain TfR levels were decreased in mice treated with TfR:BACE1, in contrast to an increasing trend of brain TfR levels when treated with biMOG Low :TfR:SarsCov (Fig. 9 C).

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