HPV and p53 Status as Precision Determinants of Head and Neck Cancer Response to DNA-PKcs Inhibition in Combination with Irradiation.

Mol Cancer Ther · 2025 · PMC11791480 · PMID 39513374

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highly significantno p-value reported

However, a dramatic and highly significant increase in the number of γH2AX and RAD51 foci after combining DNA-PKcs inhibition and IR compared with IR alone can be observed almost uniformly across all the studied cell models at later time points, especially 48 hours after treatment.

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