Cost-reduction strategy to culture patient derived bladder tumor organoids.

Except GATA3, all genes were higher expressed and highly significant (P value ≤ 0.0001) in BME group as control in compare with sodium alginate group (P Value: 0.2029) (Fig. 2 .I), which might show sodium alginate could preserve origin tissue diversity but potentially lead bladder organoid cultures toward a basal phenotype 31 .

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