Prostate Cancer Bone Metastasis: Molecular Mechanisms of Tumor and Bone Microenvironment.

2 According to the National Cancer Center of China’s 2024 National Cancer Report, there has been an increasing trend in both the incidence and mortality rates of prostate cancer in China in recent years, ranking sixth among the top ten malignant tumors in men. 3 The 2022 American Cancer Statistics Report estimated that prostate cancer would be the most common newly diagnosed cancer, accounting for 27%, and the second leading cause of cancer death, accounting for 11%. 4 Localized tumors in early-stage PCa patients can be effectively treated through surgical resection, radiotherapy, or hormone therapy.

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