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Effects of Poly-L-Lactic Acid Fillers on Inflammatory Response and Collagen Synthesis in Different Animal Models.

J Cosmet Dermatol · 2025 · PMC11799711 · PMID 39910771

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a decreasing trendno p-value reported
In guinea pigs and rabbits, the subcutaneous tissue and periosteum exhibited contrasting inflammatory response patterns, with the subcutaneous tissue initially showing a decreasing trend followed by an increasing one, whereas the periosteum initially increased and then decreased.

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