Low intensity, high frequency vibration training to improve musculoskeletal function in a mouse model of volumetric muscle loss.

Effect of vibration on in vivo active contractility and passive stiffness Plantarflexion torque about the ankle joint was ~18% lower in VML-0.6 g mice compared with VML-NoTx mice ( p = 0.030, Figure 1A ); however, when peak isometric-torque was normalized to gastrocnemius muscle-mass, a marker of muscle quality, there was only a statistical trend ( p = 0.086) for lower torque among VML-0.6 g mice ( Figure 1B ).

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