Association between Loa loa microfilaremia and anatomical hyposplenia in a rural area of the Republic of Congo: a population-based cross-sectional study.

Although not all subgroup analyses revealed significant gradient effects, the fact that aORs were consistently increased in individuals with microfilaremia, regardless of their MFD, and that the association was highly significant in those belonging to the highest MFD category, supports the hypothesis of a deleterious effect on the spleen.

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