Evaluating Activated Regulatory T Cells as a Biomarker of Chronic Allograft Inflammation in Pediatric Kidney Transplant Recipients.

Pediatr Transplant · 2025 · PMC11807789 · PMID 39924341

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a nonsignificant trendno p-value reported

Use of mammalian target of rapamycin (mTOR) with reduced tacrolimus in kidney transplant recipients led to an increase in circulating CD4 + CD25 high CD127 − CD45RA − activated Tregs, and there was a nonsignificant trend toward improved graft function [ 33 ].

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