highly significantp-value = 1 × 10 −5
Although patients were well-matched to controls in terms of age ( t -test and Bartlett test p-value = .68 and p-value = .19, comparing means and variances in age between groups, respectively), patients showed a highly significant age-related reduction in TST ( r = −.32, p-value = 1 × 10 −5 ), whereas TST and age were unrelated in controls ( p-value = .57), yielding a significant age × disease interaction ( p-value = .003).