Development of a novel prognostic signature based on cytotoxic T lymphocyte-evasion genes for hepatocellular carcinoma patient management.

Treatment strategy based on the CCG signature for HCC In the learning cohort, the CCG signature showed positive and highly significant correlations with TMB and MSI (all P < 0.05) (Fig. 6 A, B), indicating an indirect association with the efficacy of immunotherapy.

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