Global, regional, and national burden of children and adolescents with acute lymphoblastic leukemia from 1990 to 2021: a systematic analysis for the global burden of disease study 2021.

Overall, there is a trend of increasing EAPC for both incidence and prevalence as one moves from low to high-middle SDI regions, while the EAPC for deaths and DALYs exhibits a decreasing trend ( Table 1 ; Figure 1 ; Supplementary Tables S1, S2 ).

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