The effects of <i>Lepidium meyenii</i> on MSG-induced subfertility in male Wistar rats: Targeting oxidative stress, pro-inflammatory cytokines, steroidogenic enzymes, and reproductive hormones regulation.

Interestingly, spermatogenesis-associated gene family 6 (SPATA6), one of the key proteins that play an important role in sperm production and sperm motility showed a decreasing trend in the MSG group compared to the control.

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In their follow-up study, they investigated the gene expression levels of steroidogenic markers, and they observed that Maca has no obvious effect on mRNA expression of LHCGR , STAR and CYP11A1 , but there is an increasing trend [ 58 ], which is similar to the protein expression findings of the current study.

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