highly significantp < 0.001
The overall analysis of the NSND group also showed a highly significant association with a high CPS ( p < 0.001). 3.3 Association of Immunohistochemical Expression of PD ‐ L1 , PD ‐1 and Clinicohistopathologic Characteristics The analysis of associations between PD‐L1 and PD‐1 expression with clinical parameters showed a significant association between low PD‐1 expression and advanced T‐stages (T3 + T4) ( p = 0.032), as well as the presence of lymphangiosis carcinomatosa ( p = 0.008).