Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway.

Int J Mol Sci · 2025 · PMC11817368 · PMID 39940822

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Compared with HFCFD-fed WT mice, HFCFD-fed Tg mice presented significantly lower alanine aminotransferase (ALT), hepatic total cholesterol (TC), and hepatic triglyceride (TG) levels, with a decreasing trend in aspartate transaminase (AST) levels ( Table 1 , Figure 4 A,B).

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