The overall effect size (Z = 25.93, p < 0.001) indicates a highly significant effect across all combined studies, with an average myopic defocus of −2.69 D [95% CI, −2.89 D, −2.48 D] induced by orthokeratology treatment.
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Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis.
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