Barely Significant
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Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis.

J Clin Med · 2025 · PMC11818867 · PMID 39941333

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highly significantno p-value reported
The overall effect size (Z = 25.93, p < 0.001) indicates a highly significant effect across all combined studies, with an average myopic defocus of −2.69 D [95% CI, −2.89 D, −2.48 D] induced by orthokeratology treatment.

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