Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators.

In fact, reduced concentrations of IgA, IgG and IgM were seen in all MS patients who underwent apheresis ( n =6), with the decrease in IgG levels being highly significant (from 4.21 to 0.82 g/L or -81% on average, p =0.002).

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