Novel ethyl 2-hydrazineylidenethiazolidin-5-ylidene acetate clubbed with coumarinylthiazolyl pyrazole system as potential VEGFR-2 inhibitors and apoptosis inducer: synthesis, cytotoxic evaluation, cell cycle, autophagy, <i>in silico</i> ADMET and molecular docking studies.

RSC Adv · 2025 · PMC11822769 · PMID 39957832

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highly significantno p-value reported

According to the National Cancer Institute (NCI) guidelines, compounds exhibiting an IC 50 value of ≤10 μg mL −1 are regarded as demonstrating highly significant inhibitory activity.

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