Submucosal Infiltration versus Intravenous Administration of Dexamethasone in Decreasing Post-operative Inflammatory Sequelae after Third Molar Surgery - A Comparative Study.

Although after third molar removal, the overall complication rate is low and most complications are minor, third molar removal is so common that even those minor complications may be significant.[ 4 ] The factors contributing to post-operative pain, oedema and dysfunction are complex, but many of the contributing factors are related to the inflammatory process.

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It is reported that swelling may increase on the 3 rd day after surgery in patients treated with corticosteroids and there is a need to continue corticosteroid therapy for a minimum of 3 days to maintain the blood level of the drug.[ 1 40 ] It is pertinent to note that reduction of facial swelling in the IV dexamethasone group during the 2 nd , 4 th and 7 th post-operative days was statistically highly significant compared to the SM dexamethasone group, indicating that IV dexamethasone is an effective route for reducing swelling after third molar surgery.

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