A Microtubule-Associated Protein Functions in Preventing Oocytes from Evading the Spindle Assembly Checkpoint.

Adv Sci (Weinh) · 2025 · PMC11831433 · PMID 39721007

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Human oocytes, compared to those of other mammals, have a higher rate of aneuploidy, and the human oocyte's more unstable spindle and unique spindle assembly form may be significant factors, [ 23 ] although other factors cannot be ruled out, such as the lower NUSAP protein content in human oocytes compared to those of other mammals.

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