Genotypic analysis of human papillomavirus in cervical exfoliated cells from women in Zigong.

Conclusion Based on the analysis of HPV infections in cervical exfoliated cells from 48,474 gynecology patients in Zigong Fourth People’s Hospital, we conclude the following: 1From 2016 to 2024, the overall HPV infection rate showed an increasing trend, while infection rates for HPV types 6, 11, 16, and 18 exhibited a slight decline; 2Most HPV genotypes, HR-HPV-only, LR-HPV-only, mixed LR and HR-HPV, single infections, multiple infections, and the total infection rate exhibited a bimodal distribution, with peaks in young and elderly women; 3Among HPV-positive patients, HR-HPV-only infections were predominant, followed by LR-HPV-only and mixed LR and HR-HPV infections. 4Single infections remain the predominant form of HPV infection, with HPV types 52, 16, 53, and 58 being the most common genotypes.

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