Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity.

Front Immunol · 2025 · PMC11832521 · PMID 39967660

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an increasing trendno p-value reported

Although other cytokines including GM-CSF, IL-12 (p40), IL-2, and IL-17 showed an increasing trend in HFD-fed siglec-E KO mice compared to the WT mice, the increase was non-significant ( Figure 6A ).

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