highly significantP = 0.005
The result is plotted in Figure 4 , illustrating the finding that HERVK PBA increases significantly with age (r = 0.357, P = 0.002) (It can be seen in Figure 4 that there is a high PBA value; if that is removed from the analysis, the positive association between and HERVK PBA remains strong and highly significant [r = 0.326, P = 0.005], attesting to the robustness of this effect). 3.4 HLA alleles in the very old and their association with virus PBA We then analyzed the PBAs of the 13 viruses in 11/13 VOA alleles (alleles C*02:02 and C*03:02 could not be modeled by the IEDB NetMHCpan affinity tool) using a repeated-measures analysis of variance (ANOVA), where virus PBAs were the dependent variables.