At the gene level, the expression levels of endoplasmic reticulum stress-related marker genes showed an increasing trend after PMT stimulation for 6, 12, and 48 hours, but endoplasmic reticulum stress was suppressed at 24 hours ( Figure 4b ).
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The T-type voltage-gated Ca<sup>2+</sup> channel Ca<sub>V</sub>3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin.
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