Differential expression of the MYC-Notch axis drives divergent responses to the front-line therapy in central and peripheral extensive-stage small-cell lung cancer.

For OS, bone metastasis (HR: 1.49, 95% CI: 0.96–2.32, p = 0.073) was identified as a marginally significant risk factor in the univariate model. 2.3 Efficacy of the chemo‐immunotherapy group In the chemo‐immunotherapy group, the ORR and DCR for all patients were 74.4% and 94.4%, respectively.

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