Factors influencing lateral margin diagnosis challenges in Barrett's esophageal cancer: a bicenter retrospective study in Japan.

3 - 5 While squamous cell carcinoma of the esophagus remains predominant in East Asia, including Japan, the incidence of BEA has shown an increasing trend due to increased efforts in GERD and H. pylori eradication. 6 , 7 The incidence of BEA per 100,000 person-years in a certain prefecture in Japan was reported to have increased from 0.2 to 0.8 over a 30-year period between 1885 and 2014, and there is a possibility of a further increase in the future

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