Barely Significant
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Serum adropin levels as a potential biomarker for predicting diabetic kidney disease progression.

Front Endocrinol (Lausanne) · 2025 · PMC11842233 · PMID 39991732

2
hedged sentences
0.0510
closest p · 1.0× alpha
0.0960
boldest claim

The sentences

borderline significantP =0.051so close (0.05 < p ≤ 0.1)
This association remained significant even after adjusting for serum creatinine at baseline (aOR 23.003, 95% CI 1.121-471.776, P =0.042), macroalbuminuria at baseline (aOR 21.968, 95% CI 1.085-444.659, P =0.044), use of SGLT2 inhibitors (aOR 23.496, 95% CI 1.208-456.928, P =0.037), and use of statins (aOR 40.208, 95% CI 1.389-1164.178, P =0.031), but the association became borderline significant after adjusting for the use of antihypertensive agents (aOR 17.968, 95% CI 0.990-326.052, P =0.051).

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borderline significanceP = 0.096so close (0.05 < p ≤ 0.1)
After adjusting for osmolality, GFR, UACR, use of anti-hypertensive agents and use of statins, the serum adropin level showed borderline significance (adjusted odds ratio (aOR) 1.001, 95% confidence interval (CI) 1.000-1.003, P = 0.096) between subjects with diabetes and controls. 3.3.

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