Defective X-chromosome inactivation and cancer risk in women.

Commun Biol · 2025 · PMC11846847 · PMID 39987288

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highly significantno p-value reported

X-Ra was associated with moderate but highly significant and consistent reductions of XIST expression 38 , 20q ( RTEL1 ), and 8q ( MYC ) copy number gains 21 ; 8p ( CSMD1 ) deletions 26 ; lower breast cancer survival 39 and basal type 1 TNBC 27 .

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