Barely Significant
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Locus coeruleus tau is linked to successive cortical tau accumulation.

Alzheimers Dement · 2025 · PMC11848382 · PMID 39641328

1
hedged sentence
0.0560
closest p · 1.1× alpha
0.0560
boldest claim

The sentences

a trend toward significancep = .056so close (0.05 < p ≤ 0.1)
The floodlight interaction analysis revealed a trend toward significance for the interaction between global amyloid burden and LC tau levels (β = −0.403, 95% confidence interval [−0.818, 0.011], p = .056), indicating that the association between amyloid burden and memory may be moderated by LC tau, though this did not reach conventional significance.

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