Barely Significant
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Context Dependency of Hydrophobicity in Intrinsically Disordered Proteins: Insights from a New Dewetting Free Energy-Based Hydrophobicity Scale.

J Phys Chem B · 2025 · PMC11848916 · PMID 39907269

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fairly significantno p-value reported
Beyond these two AAs, though, it is clear from Figure 1 that there is a fairly significant spread in current hydrophobicity scores for every AA.

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