Barely Significant
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Local Antimicrobial Potential of Bupivacaine and Tolfenamic Acid-Loaded Ultra-High Molecular Weight Polyethylene (UHMWPE) for Orthopedic Infection.

Bioengineering (Basel) · 2025 · PMC11851508 · PMID 40001692

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an increasing trendno p-value reported
There was generally an increasing trend in cumulative BP release as the drug loading of BP increased (maximum of ~24 mg at day 21 for 20BP loaded UHMWPE).

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