Influence of orthodontic archwire (nickel-titanium versus copper-nickel-titanium) on pain in adult patients in the aligning phase of treatment with self-ligating brackets (two months of follow-up): a prospective observational pilot study.

Head Face Med · 2025 · PMC11853181 · PMID 39994811

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a slight trendno p-value reported

In the sample studied, we did not observe that there was a statistically significant relationship between the age and sex of the participants and their pain levels during the study’s follow-up period, although we observed a slight trend in which women described higher levels of pain compared with men.

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